Photocuring of aliphatic-lineal poly(glycerol adipate) with a monomer bearing thiazolium groups as a promising approach for biomedical applications
نویسندگان
چکیده
In this work, we described the combination of photocurable methacrylic monomer and poly(glycerol adipate) (PGA) macromer to form networks that can be further quaternized provide antimicrobial character. Both monomers were synthesized enzymatically. Networks with different content prepared characterized by water contact angle measurements, surface charge, soluble fractions, differential scanning calorimetry microhardness determine effect in PGA network. Methacrylic affected mechanical behavior but did not alter wettability, whereas quaternization wettability nor properties network surfaces. Finally, obtained introduced permanent cationic charges tested against Gram-positive S. aureus Gram-negative E. coli bacteria showing remarkable activity which increased Moreover, assays red blood cells demonstrated are no toxic.
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ژورنال
عنوان ژورنال: European Polymer Journal
سال: 2023
ISSN: ['0014-3057', '1873-1945']
DOI: https://doi.org/10.1016/j.eurpolymj.2023.111875